On the day of and on the day after treatment with this medicine, do not drive, use machinery, or do anything that needs mental alertness. If a negative reaction occurs, please call your veterinary office. Do not use in pets that are allergic to it, in puppies less than 3 weeks old, or kittens less than 6 weeks old. If a negative reaction occurs, please call your veterinary office. It increases the cell permeability to Ca in schistosomes, causing strong contractions and paralysis of worm musculature leading to detachment of suckers from the blood vessel walls and to dislodgement. SIDE EFFECTS: Headache, dizziness, stomach pain, nausea, tiredness, weakness, joint/muscle pain, loss of appetite, vomiting, and sweating may occur. Clipboard, Search History, and several other advanced features are temporarily unavailable. Indications, dose, contra-indications, side-effects, interactions, cautions, warnings and other safety information for PRAZIQUANTEL. Praziquantel Side Effects in Dogs. Drug efficacy; Efficacy; Egg reduction; Ethiopia; Infection; Parasite; Praziquantel; Prevalence; Schistosoma mansoni; Schistosomiasis; Schoolchildren; Side effect; Susceptibility; Thick smear. 2014 Nov 20;8(11):e3286. Otherwise, this medicine is generally considered very safe for use in dogs. It is highly advised to visit a professional vet if the symptoms of tapeworms’ infection still persist even if you already give your feline a treatment. Careers. Kramers PG, Gentile JM, Gryseels BJ, Jordan P, Katz N, Mott KE, Mulvihill JJ, Seed JL, Frohberg H. Schneeberger PHH, Coulibaly JT, Panic G, Daubenberger C, Gueuning M, Frey JE, Keiser J. Parasit Vectors. Would you like email updates of new search results? These side effects are usually mild and temporary and may be symptoms of your parasite infection and/or the dying parasites. Please enable it to take advantage of the complete set of features! Any of the uncommon side effects of using praziquantel for felines may include lethargy, pain, vomiting, and appetite loss. COVID-19 is an emerging, rapidly evolving situation. Side Effects; Products and services. Pharmacol Ther. It is highly advised to … Hence, in depth studies are recommended to clarify whether the present relatively lower cure rate is the actual cure rate of the praziquantel evaluated, treatment failure, or reduced susceptibility of the parasite. The typical side effects of the drug are abdominal pain, nausea, diarrhea, headache, skin rash and fever. License: Except as otherwise noted, this work is licensed under a Creative Commons Attribution-Noncommercial-Share Alike 4.0 License.For commercial use or customized versions, please contact biobyte solutions GmbH.. Disclaimer: The content of this database of side effects (adverse drug reactions) is intended for educational and scientific research purposes only. How to store Cysticide 6. Description: Praziquantel is a pyrazinoisoquinoline anthelmintic agent w/ a broad spectrum of activity against trematodes (flukes) and cestodes (tapeworms).It increases the cell permeability to Ca in schistosomes, causing strong contractions and paralysis of worm musculature leading to detachment of suckers from the blood vessel walls and to dislodgement. However, it is worth remembering that the side effects of Droncit are infrequent, especially when compared to other worming treatments. What Cysticide is and what it is used for Cysticide contains praziquantel and is used to treat infections caused by the larvae of pork tapeworm in the central nervous system (neurocysticercosis). Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Another side effect that can be commonly noticed in cats is excessive drooling. Author information: (1)Department of Medical Microbiology, College of Health Sciences, University of Nairobi, Nairobi. and D. caninum. Prevalence of Schistosoma mansoni infection and the therapeutic efficacy of praziquantel among school children in Manna District, Jimma Zone, southwest Ethiopia. Pharmacokinetics and drug interactions are analyzed and the low toxicity and mild side effects are stressed. OBJECTIVE: To evaluate the efficacy and side effects of praziquantel (PZQ) in the treatment of schistosomiasis in Ethiopia. It is currently the most effective drug for the treatment of schistosomiasis. Praziquantel works by causing severe spasms and paralysis of the worms' muscles. Some kinds of worms are then passed in the stool. 2020 Nov 6;9(11):920. doi: 10.3390/pathogens9110920. Infect Dis Poverty. Check with your doctor immediately if any of the following side effects occur: Incidence not known. Prevention and treatment information (HHS). It is used to treat infections of some parasite worms. Otherwise, this medicine is generally considered very safe for use in dogs. Clipboard, Search History, and several other advanced features are temporarily unavailable. Praziquantel side effects and efficacy related to Schistosoma mansoni egg loads and morbidity in primary school children in north-east Ethiopia. The cure rate showed significant association with age (χ(2)=11, P=0.004), the highest rate being observed in the 15-22 age group. After a brief mention of the history, the chemistry, th … Black, tarry stools blistering, peeling, or loosening of the skin bloody diarrhea blurred or loss of vision chest pain or discomfort chills cough dark urine diarrhea difficulty swallowing difficulty with … The heavier the parasite burden, the heavier and more frequent the side effects normally are. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Feeling tired or weak. Do not drive or operate heavy machinery until you know how praziquantel affects you. Praziquantel may result in these side effects: Vomiting; Diarrhea or loose stool; Loss of appetite; Lethargy; Pain at the injection site; Drooling in cats; Please consult your veterinarian before giving any other antihelmintic (deworming) drug or herbal supplement to your pet while on, or before giving Praziquantel. Prevention and treatment information (HHS). This site needs JavaScript to work properly. 2014 May;90(5):819-22. doi: 10.4269/ajtmh.13-0059. If your pet is very young (under 2 months), it's generally not advisable to give him praziquantel. Precautions and Side Effects. Other side-effects included dizziness (9.7%), fever (7.8%), urticaria and bloody diarrhoea. Accessibility The most commonly seen side effects of praziquantel typically include the following: Diarrhea; Vomiting; Loss of appetite; Lethargy or sedation; If you use the injectable type of praziquantel, it's not uncommon for there to be a mild inflammation or some minor pain at the point at which you've made the injection. eCollection 2014. Trop Med Int Health. Praziquantel causes adverse effects after short-term treatment. Pre-treatment prevalence of S. mansoni infection was 74.9% with geometric mean egg count of 268. Biltricide; Descriptions. US Brand Name. To evaluate the efficacy and side effects of praziquantel (PZQ) in the treatment of schistosomiasis in Ethiopia. Praziquantel may cause side effects. 2018 Mar 12;11(1):168. doi: 10.1186/s13071-018-2739-2. Upset stomach. First, a little about yourself . Gebreyesus TD, Tadele T, Mekete K, Barry A, Gashaw H, Degefe W, Tadesse BT, Gerba H, Gurumurthy P, Makonnen E, Aklillu E. Pathogens. For ethical reasons, all pupils who served as controls were treated with praziquantel after the study. 1999 Jan 15;72(1):53-63. doi: 10.1016/s0001-706x(98)00084-9. Pharmacokinetic pa-rameters with and without cimetidine are shown in Table 2. t 1/2 ranged between 1.2 and 2.7 h when praziquantel was adminis-tered alone and 1.8 to 2.4 h when it was administered with cimetidine. Mnkugwe RH, Minzi O, Kinung'hi S, Kamuhabwa A, Aklillu E. PLoS Negl Trop Dis. Praziquantel is usually avoided in pets that are under about 4 weeks of age. However, the prospect of relying on a single drug for a disease affect-ing 200 million people is an alarming situation (Cioli, 2000). Fallon PG, Mubarak JS, Fookes RE, Niang M, Butterworth AE, Sturrock RF, Doenhoff MJ. Get emergency medical help if you have signs of an allergic reaction : hives ; difficult breathing; swelling of … Praziquantel is a drug that is commonly used in veterinary medicine. Would you like email updates of new search results? Praziquantel(Biltricide) generic is an anthelmintic agent, used to treat tapeworm, schitosomal and fluke infections. Stool specimens were examined using a single Kato-Katz thick smear for Schistosoma mansoni (S. mansoni) ova. These side effects are usually mild and temporary and may be symptoms of your parasite infection and/or the dying parasites. Accessibility Jaoko WG(1), Muchemi G, Oguya FO. Description: Praziquantel is a pyrazinoisoquinoline anthelmintic agent w/ a broad spectrum of activity against trematodes (flukes) and cestodes (tapeworms). Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Children who were found positive for S. mansoni were treated with a single oral dose of PZQ at 40 mg/kg bw and interviewed for treatment-related symptoms 24 hours after drug administration. These side effects are usually mild and temporary and may be symptoms of your parasite infection and/or the dying parasites. It works partly by … PLoS Negl Trop Dis. Originally developed for veterinary applications, for humans it is a low cost, effective drug with mild side effects. doi: 10.1371/journal.pntd.0008619. When the 20 children who remained egg-positive after the second dose were each given a third dose of praziquantel, 16 (80%) … 2021 Feb 1;7(1):4. doi: 10.1186/s40794-020-00127-x. Postmarketing effects of praziquantel include: abdominal pain; allergic reaction ; bloody diarrhea; convulsions (seizures) fatigue; increased white blood cells; irregular heart beat; loss of appetite; muscle pain; rash; severe itching; sleepiness; spinning sensation ; vomiting; weakness; This document does not contain all possible side effects and others may occur. It … Epub 2014 Mar 10. Introduction Praziquantel is a systemic anthelmintic used primarily to treat worm infections. Diarrhea is an extremely common side effect of consumption of praziquantel drugs by felines. Privacy, Help Sign up now. Praziquantel results in parasitologic cure in approximately 80% of cases, but in people who are … Free E-newsletter Subscribe to Housecall. Side-effects — mainly dizziness, sleepness, abdominal distress, headache, nausea and diarrhea — were observed in 87% of the cases. Interceptor Plus Side Effects The following adverse reactions have been reported in dogs after administration of milbemycin oxime or praziquantel: vomiting, diarrhea, depression/lethargy, ataxia, anorexia, convulsions, weakness, and salivation. 83% of S. mansoni infected children showed various treatment-related symptoms, the most frequent being headache, nausea, and abdominal pain. Schistosoma mansoni: maturation rate and drug susceptibility of different geographic isolates. Methods: If any of these effects persist or worsen, tell your doctor or pharmacist promptly. There was correlation between frequencies of these side-effects and intensity of infection measured as eggs per gram of faeces. The present observations revealed relatively lower cure and egg reduction rates of the PZQ evaluated as compared to previous reports for other PZQ brands in Ethiopia. PRAZIQUANTEL (Side effects, Contraindications, Nursing considerations, Mechanism of action, Storage conditions, Indications, Route of administration) Common side effects may include: general ill feeling; headache, dizziness; nausea, stomach discomfort; fever; or rash. While it's possible that your pet might have an allergic reaction to the medicine, this situation is very rare. doi: 10.1371/journal.pntd.0003286. Dizziness. The main side-effects were abdominal pain (36.3%), headache (35.3%) and nausea (13.1%). tolerated both treatments; side effects were mild and mainly included slight dizziness and headache. Praziquantel has three unique pharmacological effects on S. japonicum and S. mansoni, i.e., stimulation of worm motor activity, spasmodic contraction of the musculature, and vesicle formation in tegument [20,21,22,23,24,25].The former two actions link the subsequent hepatic shift of the worms in vivo, while the latter is key to kill the worm. There was correlation between frequencies of these side-effects and intensity of infection measured as eggs per gram of faeces. What are the possible side effects of praziquantel (Biltricide)? Overall, the side-effects of praziquantel were mild and transient, and did not require any intervention. Description and Brand Names. Age: Tell us about yourself in a few words? Praziquantel is a drug that is commonly used in veterinary medicine. Headache. Our general interest e-newsletter keeps you up to date on a wide variety of health topics. Privacy, Help Broadline-treated cats were compared to cats treated with a spot-on product containing the worm medicines emodepside and praziquantel. Contents of the pack and other information 1. Common side effects of praziquantel include general ill feeling, headache, stomach pain, nausea, and increased temperature. While generally safe and effective when prescribed by a veterinarian, Milbemycin/Praziquantel (Milbemax®) may cause side effects in some animals. drug side effect resource. Detailed Praziquantel dosage information for adults and children. Male Female. SIDE EFFECTS: Headache, dizziness, stomach pain, nausea, tiredness, weakness, joint/muscle pain, loss of appetite, vomiting, and sweating may occur. Includes dosages for Hymenolepis nana (Dwarf Tapeworm), Taenia saginata (beef tapeworm), Schistosoma haematobium and more; plus renal, liver and dialysis adjustments. Praziquantel results in parasitologic cure in approximately 80% of cases, but in people who are … Efficacy and side effects of praziquantel in the treatment of Schistosomiasis mansoni in schoolchildren in Shesha Kekele Elementary School, Wondo Genet, Southern Ethiopia. Animals should be tested for heartworm infection before beginning prevention with … 2014 Feb 10;9(2):e88315. Side Effects and Drug Reactions. Positive impact of preventative chemotherapy during a national helminth control program: Perception and KAP. Although mild and transient side-effects were frequently observed after the first treatments, no severe systemic complaints were recorded. Praziquantel is given on and off label and by mouth or injection to treat various internal parasites. Common sideeffects include abdominal discomfort, nausea, vomiting, malaise, headache,dizziness, drowsiness, and rectal bleeding.Rarer side effects include hypersensitivity reactions, such as fever,pruritus, and eosinophilia (may be due to dead and dying parasites) (WHOEMLib). Tell your doctor if any of these symptoms are severe or do not go away: not feeling well; headache; dizziness; stomach pain; nausea; fever; itching; Some side effects can be serious. Side Effects of Praziquantel Use. PRAZIQUANTEL is an anti-infective. Belly pain. Indications. Parasit Vectors. 2018 Jul 5;7(1):73. doi: 10.1186/s40249-018-0448-x. crampi allo stomaco, gonfiore, diarrea, costipazione, nausea; un attacco; difficoltà di concentrazione; o. sudorazione fredda, irritazione della pelle. Praziquantel is an effective drug for the treatment of. Praziquantel Side Effects. The lowest GoodRx price for the most common version of generic Praziquantel is around $131.75, 73% off the average retail price of $493.82. Results: Epub 2013 Sep 14. License: Except as otherwise noted, this work is licensed under a Creative Commons Attribution-Noncommercial-Share Alike 4.0 License.For commercial use or customized versions, please contact biobyte solutions GmbH.. Disclaimer: The content of this database of side effects (adverse drug reactions) is intended for educational and scientific research purposes only. 2017 Jan 26;10(1):47. doi: 10.1186/s13071-016-1958-7. Praziquantel may result in these side effects: Vomiting; Diarrhea or loose stool; Loss of appetite; Lethargy; Pain at the injection site; Drooling in cats Efficacy and side effects of praziquantel in the treatment for Schistosoma mansoni infection in school children in Senbete Town, northeastern Ethiopia. A major weakness of praziquantel is its relative inefficacy against recent infections, a factor that may occasionally result in low cure rates in hyperendemic areas. Drug information provided by: IBM Micromedex. If you experience the following symptom, call your doctor right away: hives ; Praziquantel may cause other side effects. Praziquantel is the drug of choice for the treatment of all forms of schistosomiasis. Milbemycin/Praziquantel (Milbemax®) should not be used in animals with known hypersensitivity or allergy to the drug. Droncit works quite differently and therefore Droncit tablets can be given to a pet with food, which seems to make side effects quite rare. You may get drowsy or dizzy. The only side effect of broad-spectrum praziquantel is just temporary ataxia. Investigations on the interplays between Schistosoma mansoni, praziquantel and the gut microbiome. Efficacy of praziquantel treatment regimens in pre-school and school aged children infected with schistosomiasis in sub-Saharan Africa: a systematic review. Minor and transitory side-effects were reported for both regimens. Praziquantel may also be given at a dose of 25 mg/kg, twice or 50 mg/kg, once for one day [102,103]. Treatment-related side effects observed were transient and tolerable. Keywords: eCollection 2020 Sep. Mutapi F, Tagwireyi P, Lim R, Mangwanda B, Fourier C, Mduluza T. PLoS Negl Trop Dis. Loading... Unsubscribe from Antiparasitic Drugs? What are the possible side effects of praziquantel (Biltricide)? As described earlier, praziquantel is a safe and well tolerated drug with no serious side effects. National Library of Medicine When pets do experience praziquantel side effects, the effects are typically limited to mild gastrointestinal upset. 4. These side effects are usually mild and temporary and may be symptoms of your parasite infection and/or the dying parasites. Praziquantel Side Effects Headache, dizziness, stomach pain, nausea, tiredness, weakness, joint/muscle pain, loss of appetite, vomiting, and sweating may occur. Call your doctor at once if you have: fever, chills, sore throat, headache, body aches, tiredness, not … However, you may not notice them since they are sometimes completely destroyed in the bowels. Clinical efficacy and tolerability of praziquantel for intestinal and urinary schistosomiasis-a meta-analysis of comparative and non-comparative clinical trials. 2012 Mar;2(3):235-9. doi: 10.1016/S2221-1691(12)60049-5. Praziquantel Side Effects Headache, dizziness, stomach pain, nausea, tiredness, weakness, joint/muscle pain, loss of appetite, vomiting, and sweating may occur. Possible side effects 5. eCollection 2014. 2020 Sep 23;14(9):e0008619. Like any other injection, injectable praziquantel may also be associated with mild discomfort at the injection site. 2016 Oct 24;9(1):560. doi: 10.1186/s13071-016-1833-6. FOIA doi: 10.1371/journal.pntd.0003286. 2020 Apr 29;48:28. doi: 10.1186/s41182-020-00204-z. Prevalence of Schistosoma mansoni infection in Ethiopia: a systematic review and meta-analysis. Side effects of praziquantel typically are mild, abdominal pain is most common in treatment of intestinal schistosomiasis, and severity correlates with the burden of infection. Side effects which have been reported for Droncit include drowsiness, drooling, staggering and in only 5% of cases, nausea. Berhe N, Gundersen SG, Abebe F, Birrie H, Medhin G, Gemetchu T. Acta Trop. doi: 10.1371/journal.pone.0088315. Immediate and delayed side effects of praziquantel were observed. PLoS One. Exp Parasitol. This site needs JavaScript to work properly. Praziquantel: mechanisms of anti-schistosomal activity. Indications, dose, contra-indications, side-effects, interactions, cautions, warnings and other safety information for PRAZIQUANTEL. 1999 Jan 15;72(1):53-63. doi: 10.1016/s0001-706x(98)00084-9. Praziquantel is typically given as a one-time, single dose. Interceptor Plus is not effective against adult D. Subsequently, question is, what are the side effects of heartworm medication? 1985;29(1):129-56. doi: 10.1016/0163-7258(85)90020-8. eCollection 2020 Aug. Tesfie A, Getnet G, Abere A, Yihenew G, Belete Y, Kassa M, Gize A. Trop Med Health. COVID-19 is an emerging, rapidly evolving situation. As described earlier, praziquantel is a safe and well tolerated drug with no serious side effects. When pets do experience praziquantel side effects, the effects are typically limited to mild gastrointestinal upset. The majority of side effects develop due to the release of the contents of the parasites as they are killed and the consequent host immune reaction. Alvela-Suárez L, Velasco-Tirado V, Belhassen-Garcia M, Novo-Veleiro I, Pardo-Lledías J, Romero-Alegría A, Pérez del Villar L, Valverde-Merino MP, Cordero-Sánchez M. Am J Trop Med Hyg. Bajiro M, Dana D, Ayana M, Emana D, Mekonnen Z, Zawdie B, Garbi A, Kure A, Zeynudin A. Parasit Vectors. Side effects are uncommon but may include lack of appetite, vomiting, diarrhea, drooling, or tiredness. / Next. Immediate and delayed side effects of praziquantel were observed. Drug efficacy was determined based on cure and egg reduction rates. 2020 Aug 24;14(8):e0008494. Bethesda, MD 20894, Copyright If your cat shows severe symptoms, get them to a vet immediately to have a consultation. As with other types of drugs, more severe adverse effects may often occur. The typical side effects of the drug are abdominal pain, nausea, diarrhea, headache, skin rash and fever. FOIA The active substance praziquantel Safety of the combined use of praziquantel and albendazole in the treatment of human hydatid disease. A school-based cross-sectional survey of adverse events following co-administration of albendazole and praziquantel for preventive chemotherapy against urogenital schistosomiasis and soil-transmitted helminthiasis in Kwale County, Kenya. METHODS: In a cross-sectional study, stool specimens were collected from randomly selected 299 school children in Shesha Kekele Elementary School, Wondo Genet, Southern Ethiopia, in April 2010. CiteSeerX - Document Details (Isaac Councill, Lee Giles, Pradeep Teregowda): Abstract. In addition, it is anticipated that praziquantel usage will increase with … Four hundred and thirty six pupils in two primary schools in Kibwezi, Kenya aged between seven and sixteen years and positive for S. mansoni were treated as follows: 320 pupils with a single dose of praziquantel at 40 mg/kg body weight and 116 controls with a placebo. Clinical efficacy and tolerability of praziquantel for intestinal and urinary schistosomiasis-a meta-analysis of comparative and non-comparative clinical trials. Njenga SM, Ng'ang'a PM, Mwanje MT, Bendera FS, Bockarie MJ. Side Effects and Drug Reactions. While it's possible that your pet might have an allergic reaction to the medicine, this situation is very rare. Side effects of praziquantel typically are mild, abdominal pain is most common in treatment of intestinal schistosomiasis, and severity correlates with the burden of infection. Praziquantel can also cause dizziness. Otherwise, this medicine is generally considered very safe for use in cats. The evaluated generic PZQ produced an overall cure rate of 73.6% (P<0.000 1, OR: 8.33, CI: 5.3-13.1) and egg reduction rate of 68.2% (P=0.03, F=0.64). However, many people have no side effects or only have minor side effects. Erko B, Degarege A, Tadesse K, Mathiwos A, Legesse M. Asian Pac J Trop Biomed. It is concluded that emodepside plus praziquantel tablets are safe and effective against mature and immature stages of E. granulosus and E. multilocularis and mature stages of Taenia spp. The main side-effects were abdominal pain (36.3%), headache (35.3%) and nausea (13.1%). Berhe N, Gundersen SG, Abebe F, Birrie H, Medhin G, Gemetchu T. Acta Trop. Efficacy and safety of praziquantel 40 mg/kg in preschool-aged and school-aged children: a meta-analysis. 2013 Nov;18(11):1338-43. doi: 10.1111/tmi.12187. However, the apparent lack of teratogenic effects in mice, rats or rabbits given praziquantel while pregnant indicates that the drug may be safe to use during the classic teratogenic period of the human first trimester. Side Effects of Praziquantel Use. Conflict of interest statement: We declare that we have no conflict of interest. RARE side effects If experienced, these tend to have a Severe expression i . Praziquantel is in the anthelmintic class of medications. Please enable it to take advantage of the complete set of features! This review summarizes the main features of the drug, with special attention being given to those aspects that may be of interest to the practicing physician. Biltricide (Praziquantel): Uses, Side Effects, Precautions, Interactions, Overdose & Storage Antiparasitic Drugs. Four weeks post-treatment, stool specimens were collected from the same children and examined following the same procedure as in the pre-treatment. doi: 10.1371/journal.pntd.0008494. Praziquantel administrated at 60 mg/kg was slightly more efficacious than the 40 mg/kg standard dose. Praziquantel is efficacious against the adult stages of all human schistosome parasites, and has become the drug of choice for morbidity control of sc While it's possible that your pet might have an allergic reaction to the medicine, this reaction is quite uncommon. If your pet is very young (under 2 months), it's generally not advisable to give him praziquantel. individuals or systematic praziquantel adminis-tration (WHO, 2002). Prevalence, Intensity, and Correlates of Schistosomiasis and Soil-Transmitted Helminth Infections after Five Rounds of Preventive Chemotherapy among School Children in Southern Ethiopia. eCollection 2020. Praziquantel may also be given at a dose of 25 mg/kg, twice or 50 mg/kg, once for one day [102,103]. Hussen S, Assegu D, Tadesse BT, Shimelis T. Trop Dis Travel Med Vaccines. How was your experience with Praziquantel? 8600 Rockville Pike optic disk edema ; ventricular fibrillation, a heart rhythm disorder ; slow heartbeat ; abnormal heart rhythm Efficacy and safety of praziquantel and dihydroartemisinin piperaquine combination for treatment and control of intestinal schistosomiasis: A randomized, non-inferiority clinical trial. Fortunately, side effects are rare. Praziquantel side effects. Cancel Unsubscribe. 8600 Rockville Pike Conclusions: Effectiveness was measured by identifying adult worm segments (tapeworms) or counting worm eggs (roundworms) in faeces at day 14 after treatment. 2014 Nov 20;8(11):e3286. Bethesda, MD 20894, Copyright It works by killing sensitive worms. Abstract. PLoS Negl Trop Dis. Tell your doctor if your symptoms do not improve or if they get worse. Praziquantel side effects and efficacy related to Schistosoma mansoni egg loads and morbidity in primary school children in north-east Ethiopia. While it may be used during pregnancy, it is not recommended for use during breastfeeding. There are no known side effects of Praziquatel, but there have been studies to show it can become toxic in high volumes, which are somewhere around 40x to 50x greater than recommended dosing. Fortunately, side effects are rare. Risks and Side Effects of Praziquantel in Cats. Information about indications was extracted from the indications and usage sections of the labels. National Library of Medicine Any of the uncommon side effects of using praziquantel for felines may include lethargy, pain, vomiting, and appetite loss. Praziquantel is given on and off label and by mouth or injection to treat various internal parasites. Careers. 1997 May;86(1):29-36. doi: 10.1006/expr.1997.4149. Do not use in pets that are allergic to it, in puppies less than 3 weeks old, or kittens less than 6 weeks old. Unable to load your collection due to an error, Unable to load your delegates due to an error. Rememberthat individual reactions can occur and contact your doctor if you areexperiencing a side effect not listed here. The study showed almost 100% effectiveness against tapeworms, roundworms and hookworms for both Broadline … Visit your doctor or health care professional to check that the infection is cleared. eCollection 2014. Their incidence, intensity and duration were similar for both drugs but abdominal pain was significantly more frequent after praziquantel intake and severe dizziness was more commonly reported after oxamniquine. Unable to load your collection due to an error, Unable to load your delegates due to an error. What should I watch for? Side effects are uncommon but may include lack of appetite, vomiting, diarrhea, drooling, or tiredness. In a cross-sectional study, stool specimens were collected from randomly selected 299 school children in Shesha Kekele Elementary School, Wondo Genet, Southern Ethiopia, in April 2010. All drugs may cause side effects. Side effects in humans may include poor coordination, abdominal pain, vomiting, headache, and allergic reactions. Praziquantel side effects during treatment of Schistosoma mansoni infected pupils in Kibwezi, Kenya. No side effects of the treatment were observed. Objective: These symptoms were associated with age (P<0.001) and pre-treatment intensity of infection (P<0.05). Gli effetti collaterali comuni possono includere: malessere generale; mal di testa, vertigini; nausea, fastidio allo stomaco; febbre; o.